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IL3 Receptor alpha antibody

Anti-IL3 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX64388
Anti-IL3 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX64388
Anti-IL3 Receptor alpha antibody used in Western Blot (WB). GTX64388

Cat. No. GTX64388

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all IL3 Receptor alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human IL3RA (NP_002174.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 3 receptor subunit alpha , CD123 , IL3R , IL3RAY , IL3RX , IL3RY , hIL-3Ra

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jun 2012]

Database

Research Area

DATA IMAGES

Anti-IL3 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX64388

GTX64388 IHC-P Image

IHC-P analysis of rat lung tissue using GTX64388 IL3 Receptor alpha antibody.
Dilution : 1:100

Anti-IL3 Receptor alpha antibody used in IHC (Paraffin sections) (IHC-P). GTX64388

GTX64388 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX64388 IL3 Receptor alpha antibody.
Dilution : 1:100

Anti-IL3 Receptor alpha antibody used in Western Blot (WB). GTX64388

GTX64388 WB Image

WB analysis of A-549 cell lysate using GTX64388 IL3 Receptor alpha antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399