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United States (US)

IL5 antibody

Cat No. GTX10757

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA, Neutralizing/Inhibition

Reactivity

Human
Package
250 μg ($299)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2 μg/ml
ELISA 0.5-1.0 μg/test
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human IL expressed in Sf 21 insect cell line.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interleukin 5 , EDF , IL-5 , TRF

Cellular Localization

Secreted

Background

Human Interleukin 5 (IL5) is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide-linked homodimeric glycoprotein with 115 amino-acid residues in each chain. Known also as EDG (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two-domain structure, with each domain showing significant homology to the cytokine fold in GM-CSF, M-CSF, IL2, IL4 and growth hormone. Human and mouse IL5 have 70% amino acid sequence homology.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 299