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IL6 Receptor antibody

Anti-IL6 Receptor antibody used in Western Blot (WB). GTX37399

Cat. No. GTX37399

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all IL6 Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-2000
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived between 361-450 amino acids of human IL6 alpha Receptor

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 6 receptor , CD126 , IL-6R-1 , IL-6RA , IL6Q , IL6RA , IL6RQ , gp80

Background

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]

Database

Research Area

DATA IMAGES

Anti-IL6 Receptor antibody used in Western Blot (WB). GTX37399

GTX37399 WB Image

WB analysis of mouse brain tissue lysate using GTX37399 IL6 Receptor antibody.

REFERENCE

Application Reference

Obi AT et al. Sci Rep 2023; 13 (1) : 3253 Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions.
Application : WB
Reactivity : Human, Mouse
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REVIEW

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399