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IL6 antibody [10C12]

Anti-IL6 antibody [10C12] used in IHC (Paraffin sections) (IHC-P). GTX01893

Cat. No. GTX01893

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 10C12

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($569)
See all IL6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50

Note :

IHC-P
High temperature antigen unmasking technique. Standard ABC technique.
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Antigen Species

Human

Immunogen

A prokaryotic recombinant protein containing part of the N-terminal domain of the interleukin 6 molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 6 , BSF-2 , BSF2 , CDF , HGF , HSF , IFN-beta-2 , IFNB2 , IL-6

Cellular Localization

Secreted

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Database

Research Area

DATA IMAGES

Anti-IL6 antibody [10C12] used in IHC (Paraffin sections) (IHC-P). GTX01893

GTX01893 IHC-P Image

IHC-P analysis of human colon tissue using GTX01893 IL6 antibody [10C12]. Note cytoplasmic staining of a proportion of lymphoid cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 569