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IL6 antibody [AS16] (Biotin)

Cat. No. GTX16164

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 AS16

Isotype

 IgG1

Application

 ELISA

Reactivity

 Human
Package
100 μg ($399)
See all IL6 products

APPLICATION

Application Note

ELISA: This antibody has been used as a solution-phase antibody at 2 μg/ml in a two-site ELISA with unconjugated IL6 antibody. Typicallly, the ELISA has a working range of 0-10000 pg/ml and sensitivity 5 pg/ml with the appropriate standard. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

24 kDa. ( Note )

Product Note

Does not recognise panel of other human cytokines

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.08% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Unfortunately, this information is considered to be commercially sensitive

Purification

Protein G purified
Antibody purity > 95 % by SDS PAGE

Conjugation

Biotin

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 6 , BSF-2 , BSF2 , CDF , HGF , HSF , IFN-beta-2 , IFNB2 , IL-6

Cellular Localization

Secreted

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399