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United States (US)

IL6 antibody [B-E8]

Cat No. GTX76467

Host

Mouse

Clonality

Monoclonal

Clone Name

B-E8

Isotype

IgG1

Application

IHC-Fr, ELISA, Neutralizing/Inhibition

Reactivity

Human
Package
250 μg ($549)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent

Note :

Neutralizing/Inhibition
20pg neutralizes activity of 1U of IL-6

Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human IL-6 expressed in E. coli.

Purification

Purified by ion exchange chromatography
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Interleukin 6 , Bsf-2 , Bsf2 , Cdf , Hgf , Hsf , Ifn-Beta-2 , Ifnb2 , Il-6 , Il6

Background

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]

Database

Research Area

REFERENCE

There are currently no references for IL6 antibody [B-E8] (GTX76467). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL6 antibody [B-E8] (GTX76467). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 549