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IL6 antibody

Anti-IL6 antibody used in Western Blot (WB). GTX17623
Anti-IL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX17623
Anti-IL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX17623

Cat. No. GTX17623

Reference 6

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all IL6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
ICC/IF Assay dependent
IHC-P 1:50-400
FACS Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

24 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

KLH conjugated synthetic peptide derived from mouse IL6(130-160).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interleukin 6 , Il-6

Cellular Localization

Secreted

Background

This gene encodes a member of the interleukin family of cytokines that have important functions in immune response, hematopoiesis, inflammation and the acute phase response. The ectopic overexpression of the encoded protein in mice results in excessive plasma cells in circulation, leading to death. Mice lacking the encoded protein exhibit abnormalities in hepatic acute phase response, some immune mechanisms, bone resorption in response to estrogen, liver regeneration and wound healing. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-IL6 antibody used in Western Blot (WB). GTX17623

GTX17623 WB Image

WB analysis of various samples using GTX17623 IL6 antibody.
Dilution : 1:200
Lane 1 : mouse lung lysates
Lane 2 : protein provided by the end user lysates

Anti-IL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX17623

GTX17623 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX17623 IL6 antibody.
Dilution : 1:200

Anti-IL6 antibody used in IHC (Paraffin sections) (IHC-P). GTX17623

GTX17623 IHC-P Image

IHC-P analysis of rat liver tissue using GTX17623 IL6 antibody.
Dilution : 1:200

REFERENCE

Application Reference

Maimunah U et al. Narra J 2023; 3 (3) : e463 Correlation between interleukin-6 expression in post-mortem core liver biopsy and degree of liver injury in patients with fatal COVID-19.
Maimunah et al. Narra J 2023; 3 (3) : e463 Correlation between interleukin-6 expression in post-mortem core liver biopsy and degree of liver injury in patients with fatal COVID-19
Application : IHC-P
Reactivity : Human
W Chu et al. Biomed Pharmacother 2023; 164 : 114902 Guiqi Baizhu prescription ameliorates cytarabine-induced intestinal mucositis by targeting JAK2 to inhibit M1 macrophage polarization
Application : WB
Reactivity : Mouse
Setyo Nugroho GM et al. Ann Med Surg (Lond) 2022; 82 : 104648 Interleukin-6 (IL-6) expression of lung tissue in COVID-19 patient severity through core biopsy post mortem.
Application : IHC-P
Reactivity : Human
Hsin-Ying Lu et al. Antioxidants (Basel) 2021; 10 (5) Hydrogen Sulfide Attenuates Aortic Remodeling in Aortic Dissection Associating with Moderated Inflammation and Oxidative Stress through a NO-Dependent Pathway.
Application : IHC-P
Reactivity : Mouse
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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399