GeneTex
  • Country / Location Selection

United States (US)

IL7 Receptor alpha antibody [MAB0832]

Cat No. GTX52420

Host

Rat

Clonality

Monoclonal

Clone Name

MAB0832

Isotype

IgG2

Application

FACS, Neutralizing/Inhibition

Reactivity

Mouse
Package
200 μg ($199)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Assay dependent
Neutralizing/Inhibition Assay dependent

Note :


Blocking the binding of SB199 antibody to mouse CD127.

Neutralizing/Inhibition
Inhibiting the binding of CD127 and CD127R (IL-7 and IL-7R)

Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Mouse CD127 (IL7R alpha chain) recom-protein

Purification

Protein A/G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Cellular Localization

Membrane

Background

Interleukin-7 is a glycoptorein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is a alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for IL7 Receptor alpha antibody [MAB0832] (GTX52420). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for IL7 Receptor alpha antibody [MAB0832] (GTX52420). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 199