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IMP3 antibody [EP286]

Cat. No. GTX01720

Reference 2

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 EP286

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($489)
See all IMP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment of deparaffinized tissue with heat-induced epitope retrieval or enzymatic retrieval is recommended.
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

Positive Control

Pancreatic ductal adenocarcinoma

PROPERTIES

Form

Liquid

Buffer

Tris-HCl, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fragment within Human IMP3 Cellular Localization: Cytoplasmic

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin like growth factor 2 mRNA binding protein 3 , CT98 , IMP-3 , IMP3 , KOC , KOC1 , VICKZ3

Cellular Localization

Nucleus , Cytoplasm

Background

The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Clone Reference

2019; Well-differentiated papillary mesothelioma: A 17-year single institution experience with a series of 75 cases
Application : IHC-P
Reactivity : Human
2018; IMP3 as a prognostic biomarker in patients with malignant peritoneal mesothelioma
Application : IHC-P
Reactivity : Human
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REVIEW

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Package List Price ($)
$ 489