GeneTex

  • Country / Location Selection

United States (US)

INSM1 antibody

Anti-INSM1 antibody used in Western Blot (WB). GTX85243

Cat. No. GTX85243

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($409)
See all INSM1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

Rat Thymus Tissue Lysate(GTX24041)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1.The immunogen is located within amino acids 90 - 140 of IA-1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

INSM transcriptional repressor 1 , IA-1 , IA1

Cellular Localization

Nucleus

Background

IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100% of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.

Database

Research Area

DATA IMAGES

Anti-INSM1 antibody used in Western Blot (WB). GTX85243

GTX85243 WB Image

WB analysis of rat thymus tissue lysate using GTX85243 INSM1 antibody.
Working concentration : 1 μg/ml

REFERENCE

There are currently no references for INSM1 antibody (GTX85243). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for INSM1 antibody (GTX85243). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 409