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IP3 Receptor I antibody

Anti-IP3 Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX54759
Anti-IP3 Receptor I antibody used in Western Blot (WB). GTX54759

Cat. No. GTX54759

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all IP3 Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

313 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.3 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)RIGLLGHPPHMNVNPQQPA, corresponding to amino acid residues 2732-2750 (Intracellular, C-terminus) of rat IP3R1 (Accession  : P29994).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

inositol 1,4,5-trisphosphate receptor, type 1 , I145TR , IP3R1 , InsP3R , InsP3R1 , P400

Cellular Localization

Endoplasmic reticulum membrane

Background

This gene belongs to the Insp3 receptor family. It encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-IP3 Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX54759

GTX54759 IHC-P Image

IHC-P analysis of mouse cerebellum tissue using GTX54759 IP3 Receptor I antibody. Immunoreactivity appears in Purkinje cells (arrows in A) and their dendritic trees. In addition, axonal processes coursing through cerebellar white matter are visualized (arrow in B).

Anti-IP3 Receptor I antibody used in Western Blot (WB). GTX54759

GTX54759 WB Image

WB analysis of rat brain membrane lysate using GTX54759 IP3 Receptor I antibody preincubated with or without immunogen peptide.
Dilution : 1:2000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639