APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
SK-N-SH Cell Lysate(GTX23956)
Specificity/Sensitivity
At least two isoforms of IQSEC2 are known to exist; this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.
PROPERTIES
Form
Liquid
Buffer
PBS with 0.02% sodium azide.
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
IQSEC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IQSEC2.The immunogen is located within amino acids 1380 - 1430 of IQSEC2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
IQ motif and Sec7 domain 2 , BRAG1 , IQ-ArfGEF , MRX1 , MRX18 , MRX78
Cellular Localization
Cytoplasm
Background
This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Database
DATA IMAGES
|
GTX32143 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX32143 IQSEC2 antibody.
Working concentration : 5 μg/ml
|
|
GTX32143 WB Image
WB analysis of SK-N-SH cell lysate using GTX32143 IQSEC2 antibody.
Working concentration : 1 μg/ml
|
REFERENCE
There are currently no references for IQSEC2 antibody (GTX32143). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for IQSEC2 antibody (GTX32143). Be the first to share your experience with this product.
