GeneTex
United States (US)

IRAK3 antibody

GTX31265_871_IHC-P_20180221_18121410_522.jpg
GTX31265_873_IHC-P_20180221_18121410_534.jpg
GTX31265_872_IHC-P_20180221_18121410_294.jpg
GTX31265_2468_WB_20180221_18121410_875.jpg

Cat No. GTX31265

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

68 kDa. ( Note )

Positive Control

Mouse Spleen Tissue Lysate(GTX27937) , Rat Kidney Tissue Lysate(GTX27944) , Human Spleen Tissue Slide

Specificity/Sensitivity

IRAK-M antibody is predicted to have no cross reactivity to other members of the IRAK family.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IRAK3 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRAK3.The immunogen is located within the last 50 amino acids of IRAK3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Interleukin 1 Receptor Associated Kinase 3,Asrt5,Irakm,Irak3

Background

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES
GTX31265_871_IHC-P_20180221_18121410_522.jpg

GTX31265 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31265 IRAK3 antibody.
Working concentration : 5 μg/ml

GTX31265_873_IHC-P_20180221_18121410_534.jpg

GTX31265 IHC-P Image

IHC-P analysis of rat liver tissue using GTX31265 IRAK3 antibody.
Working concentration : 2 μg/ml

GTX31265_872_IHC-P_20180221_18121410_294.jpg

GTX31265 IHC-P Image

IHC-P analysis of rat liver tissue using GTX31265 IRAK3 antibody.
Working concentration : 10 μg/ml

GTX31265_2468_WB_20180221_18121410_875.jpg

GTX31265 WB Image

WB analysis of (M) mouse spleen and (R) rat liver tissue lysates using GTX31265 IRAK3 antibody.
Working concentration : 1 μg/ml

Package List Price ($)
$ 339