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IRF1 antibody

Orthogonal
Anti-IRF1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55681
Anti-IRF1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55681
Anti-IRF1 antibody used in Western Blot (WB). GTX55681
Anti-IRF1 antibody used in Western Blot (WB). GTX55681

Cat. No. GTX55681

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all IRF1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:100
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide of human IRF1

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interferon regulatory factor 1 , IRF-1 , MAR

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-IRF1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55681

GTX55681 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX55681 IRF1 antibody.
Blue : DAPI
Dilution : 1:100

Anti-IRF1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55681

GTX55681 IHC-P Image

IHC-P analysis of human colon tissue using GTX55681 IRF1 antibody.
Dilution : 1:100

Anti-IRF1 antibody used in Western Blot (WB). GTX55681

GTX55681 WB Image

Orthogonal

WB analysis of C2C12 cell lysates using GTX55681 IRF1 antibody.
Lane 1 : C2C12 cells
Lane 2 : C2C12 cells treated with 50 ng/mL IFN-gamma for 8 hrs
Loading : 25 μg per lane
Dilution : 1:1000

Anti-IRF1 antibody used in Western Blot (WB). GTX55681

GTX55681 WB Image

WB analysis of rat spleen tissue lysates using GTX55681 IRF1 antibody.
Loading : 25 μg per lane
Dilution : 1:1000

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399