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IRF4 / MUM1 antibody

Anti-IRF4 / MUM1 antibody used in Western Blot (WB). GTX66692
Anti-IRF4 / MUM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66692

Cat No. GTX66692

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 262-318 of Human IRF4 / MUM1.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

interferon regulatory factor 4 , LSIRF , MUM1 , NF-EM5 , SHEP8

Cellular Localization

Nucleus

Background

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010]

Database

Research Area

DATA IMAGES

Anti-IRF4 / MUM1 antibody used in Western Blot (WB). GTX66692

GTX66692 WB Image

WB analysis of various samples using GTX66692 IRF4 / MUM1 antibody.
Lane1 : HEK293T whole cell lysate
Lane2 : Raw264.7 whole cell lysate
Lane3 : PC12 whole cell lysate
Dilution : 1:500

Anti-IRF4 / MUM1 antibody used in IHC (Paraffin sections) (IHC-P). GTX66692

GTX66692 IHC-P Image

IHC-P analysis of human tonsil carcinoma tissue using GTX66692 IRF4 / MUM1 antibody.
Left : Primary antibody
Right : Negative control
Dilution : 1:50

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf