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IRS1 antibody

Anti-IRS1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31717
Anti-IRS1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31717
Anti-IRS1 antibody used in Western Blot (WB). GTX31717

Cat. No. GTX31717

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all IRS1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 4 μg/mL
ICC/IF 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

132 kDa. ( Note )

Positive Control

PC-3 Cell Lysate(GTX23954) , P815 Cell Lysate(GTX27185) , P815 Cell Slide(GTX25547)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IRS-1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human IRS-1.The immunogen is located within amino acids 910 - 960 of IRS-1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887624

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin receptor substrate 1 , HIRS-1

Background

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-IRS1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31717

GTX31717 ICC/IF Image

ICC/IF analysis of P815 cells using GTX31717 IRS1 antibody.
Working concentration : 2 μg/ml

Anti-IRS1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31717

GTX31717 ICC/IF Image

ICC/IF analysis of P815 cells using GTX31717 IRS1 antibody.
Working concentration : 2 μg/ml

Anti-IRS1 antibody used in Western Blot (WB). GTX31717

GTX31717 WB Image

WB analysis of PC-3 cell lysate using GTX31717 IRS1 antibody.
Working concentration : (A) 1, (B) 2, and (C) 4 μg/ml

REFERENCE

Application Reference

Choi KM et al. Obesity (Silver Spring) 2018; (Epub) 3,3'-diindolylmethane enhances glucose uptake through activation of * signaling in 3t3-l1 adipocytes.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399