GeneTex
United States (US)

IRS1 (phospho Ser307) antibody

GTX32202_20190131_WB_19013101_252.jpg
GTX32202_20190131_IHC-P_19013102_866.jpg

Cat No. GTX32202

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

132 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of IRS1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Insulin Receptor Substrate 1,Hirs-1,Irs1

Background

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES
GTX32202_20190131_WB_19013101_252.jpg

GTX32202 WB Image

WB analysis of insulin-treated HEK293T (A) whole cell lysates using GTX32202 IRS1 (phospho Ser307) antibody.

GTX32202_20190131_IHC-P_19013102_866.jpg

GTX32202 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX32202 IRS1 (phospho Ser307) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Package List Price ($)
$ 319