Form
Liquid
Buffer
Serum
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
KLH-conjugated synthetic peptides corresponding to the following three regions of human IZUMO1:
[A] C+KSLEKDYLPGHLDA
[B] C+TQVPKEKATDSRQQ
[C] C+ATTESSISLQPLQ
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
izumo sperm-egg fusion 1 , IZUMO , OBF
Cellular Localization
Cell membrane
Background
The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]
Database
Research Area