GeneTex
United States (US)

IZUMO1 antibody

GTX31952_3100_WB_20180221_18121410_583.jpg
GTX31952_1638_IHC-P_20180221_18121410_515.jpg

Cat No. GTX31952

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

Human Testis Tissue Lysate(GTX15374) , Human Testis Tissue Slide(GTX21748)

Specificity/Sensitivity

IZUMO1 antibody is human specific. At least four isoforms of IZUMO1 are known to exist; this antibody will detect the two longest isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

IZUMO1 antibody was raised against an 18 amino acid peptide near the center of human IZUMO1.The immunogen is located within amino acids 170 - 220 of IZUMO1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Izumo Sperm-Egg Fusion 1,Izumo,Obf,Izumo1

Background

The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]

Database

Research Area

DATA IMAGES
GTX31952_3100_WB_20180221_18121410_583.jpg

GTX31952 WB Image

WB analysis of human testis tissue lysate using GTX31952 IZUMO1 antibody.
Working concentration : 1 μg/ml

GTX31952_1638_IHC-P_20180221_18121410_515.jpg

GTX31952 IHC-P Image

IHC-P analysis of human testis tissue using GTX31952 IZUMO1 antibody.
Working concentration : 2.5 μg/ml

Package List Price ($)
$ 329