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Insulin Receptor antibody [07]

Anti-Insulin Receptor antibody [07] used in IHC (Paraffin sections) (IHC-P). GTX02077
Anti-Insulin Receptor antibody [07] used in IHC (Paraffin sections) (IHC-P). GTX02077

Cat No. GTX02077

Host

Mouse

Clonality

Monoclonal

Clone Name

07

Isotype

IgG1

Application

IHC-P

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:100-1:500
Not tested in other applications.

Calculated MW

156 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2 μm filtered PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human Insulin Receptor / INSR / CD220 protein

Purification

Purified by Protein A

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

insulin receptor , CD220 , HHF5

Cellular Localization

Cell membrane; Single-pass type I membrane protein

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-Insulin Receptor antibody [07] used in IHC (Paraffin sections) (IHC-P). GTX02077

GTX02077 IHC-P Image

IHC-P analysis of human placenta tissue section using GTX02077 Insulin Receptor antibody [07].
Dilution : 1:200

Anti-Insulin Receptor antibody [07] used in IHC (Paraffin sections) (IHC-P). GTX02077

GTX02077 IHC-P Image

IHC-P analysis of human kidney tissue section using GTX02077 Insulin Receptor antibody [07].
Dilution : 1:200

REFERENCE

There are currently no references for Insulin Receptor antibody [07] (GTX02077). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Insulin Receptor antibody [07] (GTX02077). Be the first to share your experience with this product.