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Insulin antibody [8E2] (HRP)

Cat. No. GTX40914

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 8E2

Isotype

 IgG1

Reactivity

 Human, Bovine, Pig
Package
200 μg ($399)
See all Insulin products

APPLICATION

Calculated MW

12 kDa. ( Note )

Product Note

Cross-reacts with human proinsulin, bovine insulin (30% ) and porcine insulin. Does notcross-react with free C-peptide.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

1.40 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified Human Insulin

Purification

Protein A purified

Conjugation

Horseradish peroxidase(HRP)

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10

Cellular Localization

Secreted

Background

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Proclin.pdf
Package List Price ($)
$ 399