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Insulin antibody [IRDN/794]

Anti-Insulin antibody [IRDN/794] used in IHC (Paraffin sections) (IHC-P). GTX34798
Anti-Insulin antibody [IRDN/794] used in IHC (Paraffin sections) (IHC-P). GTX34798

Cat. No. GTX34798

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IRDN/794

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human, Mouse, Rat, Bovine, Pig
Package
100 μg ($529)
See all Insulin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2μg/ml for 30 minutes at RT

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

Product Note

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Recombinant INS protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

IDDM , IDDM1 , IDDM2 , ILPR , INS , IRDN , MODY10 , insulin , Insulin

Cellular Localization

Secreted

Background

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2019]

Database

Research Area

DATA IMAGES

Anti-Insulin antibody [IRDN/794] used in IHC (Paraffin sections) (IHC-P). GTX34798

GTX34798 IHC-P Image

IHC-P analysis of rat pancreas tissue using GTX34798 Insulin antibody [IRDN/794].

Anti-Insulin antibody [IRDN/794] used in IHC (Paraffin sections) (IHC-P). GTX34798

GTX34798 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX34798 Insulin antibody [IRDN/794].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529