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Insulin antibody [IRDN/805]

Anti-Insulin antibody [IRDN/805] used in IHC (Paraffin sections) (IHC-P). GTX34799

Cat No. GTX34799

Host

Mouse

Clonality

Monoclonal

Clone Name

IRDN/805

Isotype

IgG1

Application

IHC-P

Reactivity

Human, Mouse, Rabbit, Bovine, Pig
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1-2μg/ml for 30 minutes at RT
Not tested in other applications.

Calculated MW

12 kDa. ( Note )

Specificity/Sensitivity

Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide.
We do not recommend use of this product for Rat.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA, 0.05% sodium azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Recombinant INS protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

IDDM , IDDM1 , IDDM2 , ILPR , INS , IRDN , MODY10 , insulin , Insulin

Cellular Localization

Secreted

Background

This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2019]

Database

Research Area

DATA IMAGES

Anti-Insulin antibody [IRDN/805] used in IHC (Paraffin sections) (IHC-P). GTX34799

GTX34799 IHC-P Image

IHC-P analysis of human pancreas tissue using GTX34799 Insulin antibody [IRDN/805].

REFERENCE

There are currently no references for Insulin antibody [IRDN/805] (GTX34799). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Insulin antibody [IRDN/805] (GTX34799). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf