GeneTex
  • Country / Location Selection

United States (US)

Integrin alpha 2 antibody [AK7]

Cat No. GTX76464

Host

Mouse

Clonality

Monoclonal

Clone Name

AK7

Isotype

IgG1

Application

IHC-Fr, FACS, Neutralizing/Inhibition

Reactivity

Human, Baboon, Cynomolgus monkey, Rhesus Monkey
Package
100 μg ($299)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr 1/500-1/1,000
FACS 1/50-1/100
Neutralizing/Inhibition Assay dependent

Note :

IHC-Fr
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. Recommend the use of acetone fixation for frozen sections.

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.

Neutralizing/Inhibition
Mouse anti Human CD49b antibody, clone AK7 inhibits cell attachment to collagen.

Not tested in other applications.

Calculated MW

129 kDa. ( Note )

Specificity/Sensitivity

Clone AK7 inhibits cell attachment to collagen.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Integrin Subunit Alpha 2 , Br , Cd49B , Gpia , Hpa-5 , Vla-2 , Vlaa2 , Itga2

Background

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Database

Research Area

REFERENCE

There are currently no references for Integrin alpha 2 antibody [AK7] (GTX76464). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Integrin alpha 2 antibody [AK7] (GTX76464). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 299