Integrin alpha 2 antibody [HMa2] (APC)

Cat. No. GTX01474-07
References 4
Cat. No.  GTX01474-07
Anti-Integrin alpha 2 antibody [HMa2] (APC) used in Flow cytometry (FACS). GTX01474-07
GTX01474-07 FACS Image

FACS analysis of mouse C57Bl/6 splenocytes using GTX01474-07 Integrin alpha 2 antibody [HMa2] (APC).
Right panel : co-stained with Integrin alpha 2 antibody [HMa2] (APC) and Mouse NK1.1 antibody (FITC)
Left panel : co-stained with isotype control and Mouse NK1.1 antibody (FITC)
antibody amount : 0.125 μg (5 μl)

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Anti-Integrin alpha 2 antibody [HMa2] (APC) used in Flow cytometry (FACS). GTX01474-07
  • Host
    Armenian Hamster
  • Clonality
    Monoclonal
  • Clone Name
    HMa2
  • Isotype
    IgG
  • Applications
    FACS
  • Reactivity
    Mouse
Summary
The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin αfamily. CD49b, also known as integrin αalpha2, associates non-covalently with CD29 (integrin αbeta1) to form the VLA-2 heterodimer. VLA-2 integrin αs function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.
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