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Integrin alpha 2 antibody

KO/KD
Anti-Integrin alpha 2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX35237
Anti-Integrin alpha 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35237
Anti-Integrin alpha 2 antibody used in Western Blot (WB). GTX35237
Anti-Integrin alpha 2 antibody used in Western Blot (WB). GTX35237
Anti-Integrin alpha 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35237

Cat. No. GTX35237

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Integrin alpha 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

129 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein of human ITGA2

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887750

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha 2 , BR , CD49B , GPIa , HPA-5 , VLA-2 , VLAA2

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Database

Research Area

DATA IMAGES

Anti-Integrin alpha 2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX35237

GTX35237 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX35237 Integrin alpha 2 antibody.
Blue : DAPI
Dilution : 1:100

Anti-Integrin alpha 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35237

GTX35237 IHC-P Image

IHC-P analysis of rat brain tissue using GTX35237 Integrin alpha 2 antibody.
Dilution : 1:100

Anti-Integrin alpha 2 antibody used in Western Blot (WB). GTX35237

GTX35237 WB Image

KO/KD

WB analysis of normal (control) and knockout (KO) HeLa cell lysate using GTX35237 Integrin alpha 2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Integrin alpha 2 antibody used in Western Blot (WB). GTX35237

GTX35237 WB Image

WB analysis of various sample lysates using GTX35237 Integrin alpha 2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Integrin alpha 2 antibody used in IHC (Paraffin sections) (IHC-P). GTX35237

GTX35237 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX35237 Integrin alpha 2 antibody.
Dilution : 1:100

REFERENCE

Application Reference

Gaballa R et al. Cancers (Basel) 2020; 12 (8) Exosomes-Mediated Transfer of Itga2 Promotes Migration and Invasion of Prostate Cancer Cells by Inducing Epithelial-Mesenchymal Transition.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399