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Integrin alpha 3 antibody

Cat. No. GTX40141

Host

 Mouse

Clonality

 Monoclonal

Isotype

 IgG1

Application

 IHC-Fr, IHC (Formalin)

Reactivity

 Human
Package
100 μg ($399)
See all Integrin alpha 3 products

APPLICATION

Application Note

FuncS: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

117 kDa. ( Note )

Product Note

Specific to alpha 3 integrin. IA3 is useful for studies on inhibition of cell-cell adhesion and cell-substrate adhesion.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Cell preparation: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha 3 , CD49C , FRP-2 , GAP-B3 , GAPB3 , ILNEB , MSK18 , VCA-2 , VL3A , VLA3a

Cellular Localization

Cell membrane

Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]

Database

Research Area

REFERENCE

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REVIEW

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Package List Price ($)
$ 399
Custom Conjugations