APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Dilution |
| Assay dependent |
| 1/50-1/100 |
| Assay dependent |
|
Note :
FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
|
Not tested in other applications.
Calculated MW
Product Note
Clone 44H6 is reported to induce homotypic aggregation of pre-B cell lines including HOON and NALM-6 (Letarte et al. 1993).
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
HOON pre-B leukaemia cell line.
Purification
Purified by ion exchange chromatography
From tissue culture supernatant
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
integrin subunit alpha 4 , CD49D , IA4
Cellular Localization
Membrane; Single-pass type I membrane protein
Background
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Database
Research Area
DATA IMAGES
![Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962](/templates/default/js/lightbox/images/loading.gif "Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962")
|
GTX41962 FACS Image
FACS analysis of human peripheral blood lymphocytes using GTX41962 Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free).
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REFERENCE
There are currently no references for Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) (GTX41962). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) (GTX41962). Be the first to share your experience with this product.
![Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962](/upload/website/prouct_img/small/GTX41962/GTX41962_4132_FACS_18121410_635.jpg "Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962")
![Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962](/upload/website/prouct_img/normal/GTX41962/GTX41962_4132_FACS_18121410_635.jpg "Anti-Integrin alpha 4 antibody [44H6] (Low endotoxin, azide free) used in Flow cytometry (FACS). GTX41962")