Integrin alpha 4 antibody [9F10] (PE)

Cat. No. GTX01494-08
References 1
Cat. No.  GTX01494-08
Anti-Integrin alpha 4 antibody [9F10] (PE) used in Flow cytometry (FACS). GTX01494-08
GTX01494-08 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX01494-08 Integrin alpha 4 antibody [9F10] (PE).
Solid lone : primary antibody
Dashed line : isotype control
antibody amount : 0.25 μg (5 μl)

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Anti-Integrin alpha 4 antibody [9F10] (PE) used in Flow cytometry (FACS). GTX01494-08
  • Host
    Mouse
  • Clonality
    Monoclonal
  • Clone Name
    9F10
  • Isotype
    IgG1
  • Applications
    FACS
  • Reactivity
    Human
Summary
The 9F10 monoclonal antibody reacts with human CD49d, a 150kD integral membrane protein that is also known as integrin αalpha4 (ITGA4). Together with integrin αbeta1 (CD29), CD49d forms the VLA-4 heterodimer that serves as a receptor for fibronectin and VCAM-1. VLA-4 is widely expressed on lymphocytes, monocytes, thymocytes, and NK cells. CD49d can also dimerize with integrin αbeta7 to form a receptor that binds the mucosal vascular addressin molecule, MAdCAM-1. CD49d is involved in cellular adhesion to other cells as well as extracellular matrix.
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