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Integrin alpha 6 antibody [450-30A] (FITC)

Anti-Integrin alpha 6 antibody [450-30A] (FITC) used in Flow cytometry (FACS). GTX75045

Cat. No. GTX75045

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 450-30A

Isotype

 IgG1

Application

 FACS

Reactivity

 Human, Rabbit
Package
100 μg ($399)
See all Integrin alpha 6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

127 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

integrin a6b4 purified from A431 cells

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_376583

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha 6 , CD49f , ITGA6B , VLA-6

Cellular Localization

Cell membrane

Background

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Database

Research Area

DATA IMAGES

Anti-Integrin alpha 6 antibody [450-30A] (FITC) used in Flow cytometry (FACS). GTX75045

GTX75045 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX75045 Integrin alpha 6 antibody [450-30A] (FITC).

REFERENCE

Application Reference

Lee TC et al. PLoS One 2014; 9 (11) : e111390 Comparison of Surface Markers between Human and Rabbit Mesenchymal Stem Cells.
Application : FACS
Reactivity : Human, Rabbit
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399