APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500~1:1000 |
Not tested in other applications.
Calculated MW
Product Note
Integrin alpha 6 (cleaved Glu942) antibody detects endogenous levels of fragment of activated ITGA6 resulting from cleavage adjacent to Glu942.
PROPERTIES
Form
Liquid
Buffer
PBS, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human Integrin alpha 6 (923-972).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
CD49f , ITGA6 , ITGA6B , VLA6 , integrin subunit alpha 6 , Integrin alpha 6 , Integrin α6
Cellular Localization
Cell membrane,Cell membrane
Background
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX86906 WB Image
WB analysis of HeLa cells treated with etoposide 25uM (24h) lysate using GTX86906 Integrin alpha 6 (cleaved Glu942) antibody. The lane on the right is blocked with the synthesized peptide.
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REFERENCE
There are currently no references for Integrin alpha 6 (cleaved Glu942) antibody (GTX86906). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Integrin alpha 6 (cleaved Glu942) antibody (GTX86906). Be the first to share your experience with this product.