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Integrin alpha E antibody [ITGAE/3904R]

Anti-Integrin alpha E antibody [ITGAE/3904R] used in IHC (Paraffin sections) (IHC-P). GTX02653

Cat. No. GTX02653

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 ITGAE/3904R

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human
Package
100 μg ($529)
See all Integrin alpha E products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1-2 μg/ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

130 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human ITGAE protein fragment

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit alpha E , CD103 , HUMINAE

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin alpha E antibody [ITGAE/3904R] used in IHC (Paraffin sections) (IHC-P). GTX02653

GTX02653 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX02653 Integrin alpha E antibody [ITGAE/3904R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 529