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Integrin beta 1 / CD29 antibody [4B7R] (FITC)

Anti-Integrin beta 1 / CD29 antibody [4B7R] (FITC) used in Flow cytometry (FACS). GTX75616

Cat. No. GTX75616

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4B7R

Isotype

 IgG1

Application

 FACS

Reactivity

 Human
Package
50 μg ($329)
See all Integrin beta 1 / CD29 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
FACS Neat

Note :

FACS
Use 10μl of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

88 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Occular melanoma cell line V+B2.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Fluorescein isothiocyanate (FITC)

RRID

AB_376929

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 1 , CD29 , FNRB , GPIIA , MDF2 , MSK12 , VLA-BETA , VLAB

Cellular Localization

Cell membrane , Cell junction

Background

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin beta 1 / CD29 antibody [4B7R] (FITC) used in Flow cytometry (FACS). GTX75616

GTX75616 FACS Image

FACS analysis of human peripheral blood lymphocytes using GTX75616 Integrin beta 1 / CD29 antibody [4B7R] (FITC).

REFERENCE

Application Reference

Su LJ et al. Sci Rep 2017; 7 : 45607 Fluorescent nanodiamonds enable quantitative tracking of human mesenchymal stem cells in miniature pigs.
Reactivity : Human

Clone Reference

Itou J et al. Biochim Biophys Acta 2016; 1864 (1):76-88 The Sal-like 4 - integrin α6β1 network promotes cell migration for metastasis via activation of focal adhesion dynamics in basal-like breast cancer cells.
Ueda S et al. J Clin Immunol 2010; 30 (6):861-71 Up-regulation of ?1 integrin on tonsillar T cells and its induction by in vitro stimulation with α-streptococci in patients with pustulosis Palmaris et Plantaris.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 329