APPLICATION
Application Note
FACS: Use at an assay dependent dilution. IF: 1/125 - 1/250. IHC-P: 1/125 - 1/250. IP: Use at 2μg/mg of lysate. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Positive Control
Human spleen, thymus or tonsil
Product Note
Specific for integrin beta-1 subunit or CD29, which runs at 110 kDa non-reduced and at 130 kDa reduced.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human ocular melanoma cell line V + B2
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
integrin subunit beta 1 , CD29 , FNRB , GPIIA , MDF2 , MSK12 , VLA-BETA , VLAB
Cellular Localization
Cell membrane , Cell junction
Background
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
REFERENCE
There are currently no references for Integrin beta 1 / CD29 antibody (GTX20035). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Integrin beta 1 / CD29 antibody (GTX20035). Be the first to share your experience with this product.