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Integrin beta 3 antibody [Y2/51]

Anti-Integrin beta 3 antibody [Y2/51] used in IHC (Paraffin sections) (IHC-P). GTX34801

Cat. No. GTX34801

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 Y2/51

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr, FACS

Reactivity

 Human
Package
100 μg ($529)
See all Integrin beta 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1-2μg/ml
IHC-P 1-2μg/ml for 30 minutes at RT
IHC-Fr 1-2μg/ml for 30 minutes at RT
FACS 0.5-1μg/10⁶ cells in 0.1ml

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Immunogen

Phytohemagglutinin (PHA)-stimulated peripheral blood cells

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

BDPLT16 , BDPLT2 , CD61 , GP3A , GPIIIa , GT , ITGB3 , integrin subunit beta 3 , Integrin beta3

Cellular Localization

Cell membrane,Cell projection,Lamellipodium membrane,Cell junction,Focal adhesion

Background

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin beta 3 antibody [Y2/51] used in IHC (Paraffin sections) (IHC-P). GTX34801

GTX34801 IHC-P Image

IHC-P analysis of human spleen tissue using GTX34801 Integrin beta 3 antibody [Y2/51].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 529