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Integrin beta 3 antibody

Anti-Integrin beta 3 antibody used in Western Blot (WB). GTX50435
Anti-Integrin beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX50435

Cat. No. GTX50435

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Integrin beta 3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

87 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around aa. 771~775 (P-L-Y-K-E) derived from human Integrin beta 3.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_11173003

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

integrin subunit beta 3 , BDPLT16 , BDPLT2 , CD61 , GP3A , GPIIIa , GT

Cellular Localization

Cell membrane

Background

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin beta 3 antibody used in Western Blot (WB). GTX50435

GTX50435 WB Image

WB analysis of extracts from HL-60 and HT-29 cells using GTX50435 Integrin beta 3 antibody.

Anti-Integrin beta 3 antibody used in IHC (Paraffin sections) (IHC-P). GTX50435

GTX50435 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX50435 Integrin beta 3 antibody.
Left : Primary antibody
Right : Primary antibody pre-incubated with the antigen specific peptide

REFERENCE

Application Reference

Smilde BJ et al. Int J Cardiol 2016; 216 : 58-65 Colchicine aggravates coxsackievirus B3 infection in mice.
Application : IHC-P
Reactivity : Mouse
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399