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Integrin beta 4 antibody [JM11-06]

Recombinant antibody
Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053
Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053
Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053
Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053
Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053

Cat No. GTX01053

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 JM11-06

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($369)
See all Integrin beta 4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000-1:2000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

202 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1x TBS (pH7.4), 1% BSA, 40% glycerol, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

integrin subunit beta 4,CD104,GP150,ITGB4

Cellular Localization

Cell membrane,Cell junction,Hemidesmosome

Background

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053

GTX01053 WB Image

A549 whole cell extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Integrin beta 4 antibody [JM11-06] (GTX01053) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053

GTX01053 IHC-P Image

IHC-P analysis of human breast cancer tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].

Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053

GTX01053 IHC-P Image

IHC-P analysis of mouse colon tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].

Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053

GTX01053 IHC-P Image

IHC-P analysis of human pancreas tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].

Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053

GTX01053 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].

REFERENCE

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REVIEW

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Package List Price ($)
$ 369