APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000-1:2000 |
| 1:50-1:200 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
1x TBS (pH7.4), 1% BSA, 40% Glycerol
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant protein
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
integrin subunit beta 4 , CD104 , GP150 , ITGB4
Cellular Localization
Cell membrane,Cell junction,Hemidesmosome
Background
Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053](/templates/default/js/lightbox/images/loading.gif "Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053")
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GTX01053 WB Image
A549 whole cell extract (50 μg) was separated by 7.5% SDS-PAGE, and the membrane was blotted with Integrin beta 4 antibody [JM11-06] (GTX01053) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
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GTX01053 WB Image
Mouse tissue extract (50 μg) was separated by 5% SDS-PAGE, and the membrane was blotted with Integrin beta 4 antibody [JM11-06] (GTX01053) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced.
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GTX01053 IHC-P Image
IHC-P analysis of human breast cancer tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].
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GTX01053 IHC-P Image
IHC-P analysis of mouse colon tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].
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GTX01053 IHC-P Image
IHC-P analysis of human pancreas tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].
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GTX01053 IHC-P Image
IHC-P analysis of human tonsil tissue section using GTX01053 Integrin beta 4 antibody [JM11-06].
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REFERENCE
There are currently no references for Integrin beta 4 antibody [JM11-06] (GTX01053). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Integrin beta 4 antibody [JM11-06] (GTX01053). Be the first to share your experience with this product.
![Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_HK0213_20200214_WB_20031623_916.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_HK0213_20200814_WB_M_spleen_20082000_535.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_20200303_IHC-P_334_20030422_127.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_20200303_IHC-P_337_20030422_723.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_20200303_IHC-P_336_20030422_110.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/small/GTX01053/GTX01053_20200303_IHC-P_335_20030422_342.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_HK0213_20200214_WB_20031623_916.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_HK0213_20200814_WB_M_spleen_20082000_535.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in Western Blot (WB). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_20200303_IHC-P_334_20030422_127.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_20200303_IHC-P_337_20030422_723.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_20200303_IHC-P_336_20030422_110.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")
![Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053](/upload/website/prouct_img/normal/GTX01053/GTX01053_20200303_IHC-P_335_20030422_342.jpg "Anti-Integrin beta 4 antibody [JM11-06] used in IHC (Paraffin sections) (IHC-P). GTX01053")