GeneTex
  • Country / Location Selection

United States (US)

Interferon beta antibody [7K51]

Cat No. GTX52790

Host

Mouse

Clonality

Monoclonal

Clone Name

7K51

Isotype

IgG1

Application

WB, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant INFβ

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

IFB , IFF , IFNB , IFNB1 , IFNbeta , interferon beta 1 , Interferon beta , IFN beta , IFN-β

Cellular Localization

Secreted

Background

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015]

Database

Research Area

REFERENCE

There are currently no references for Interferon beta antibody [7K51] (GTX52790). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Interferon beta antibody [7K51] (GTX52790). Be the first to share your experience with this product.
SDS
PBS.pdf