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Interferon gamma Receptor 1 antibody [BB1E2]

Cat. No. GTX11285

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 BB1E2

Isotype

 IgG2a

Application

 WB, IHC-Fr, FACS, ELISA

Reactivity

 Human, Bovine
Package
100 μg ($399)
See all Interferon gamma Receptor 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1μg/ml
IHC-Fr 1-10μg/ml
FACS 1-10μg/ml
ELISA 1μg/ml

Note :

IHC-Fr
Recommend the use of acetone fixation for frozen sections.

FACS
Use 1μg of the suggested working dilution to label 106 cells in 100μl.
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Product Note

The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein of the extracellular part of the human interferon-gamma receptor (AA: Ala17-Gly245) conjugated to 11 AA of the c-myc proto-oncogene (for affinity purification).

Purification

Purified by ion exchange chromatography

Conjugation

Unconjugated

RRID

AB_367800

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interferon gamma receptor 1 , CD119 , IFNGR , IMD27A , IMD27B

Cellular Localization

Cell membrane

Background

This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

Application Reference

Ye J et al. Front Oncol 2019; 9 : 1251 miR-4666-3p and miR-329 Synergistically Suppress the Stemness of Colorectal Cancer Cells via Targeting TGF-帣/Smad Pathway.
Application : FACS
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399