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Interferon gamma antibody [IFNG/466]

Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794
Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794
Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794

Cat No. GTX34794

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IFNG/466

Isotype

 IgG2b

Application

 ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($429)
See all Interferon gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 0.5-1ug/ml
IHC-P 1-2ug/ml for 30 minutes at RT

Note :

IHC-P
Boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Specificity/Sensitivity

Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-g and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-g. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-a/b (type I interferon).

PROPERTIES

Form

Liquid

Buffer

10mM PBS with 0.05% BSA, 0.05% azide (Please contact us for PBS only format)

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml

Antigen Species

Human

Immunogen

Purified recombinant human IFN-gamma

Purification

Ab purified from Bioreactor Concentrate by Protein A/G

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Interferon Gamma , Ifg , Ifi , Ifng

Background

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794

GTX34794 IHC-P Image

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)

Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794

GTX34794 IHC-P Image

Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)

Anti-Interferon gamma antibody [IFNG/466] used in IHC (Paraffin sections) (IHC-P). GTX34794

GTX34794 IHC-P Image

Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Interferon gamma Monoclonal Antibody (IFNG/466)

REFERENCE

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REVIEW

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Package List Price ($)
$ 429