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Interferon gamma antibody

Cat. No. GTX10743

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, Neutralizing/Inhibition

Reactivity

 Mouse
Package
25 μg ($399)
See all Interferon gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

Product Note

The antibody shows <1% cross-reactivity with recombinant human IFN-γ.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.4, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

recombinant mouse IFN-γ.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interferon gamma , IFN-g , Ifg

Cellular Localization

Secreted

Background

Interferon gamma (IFNG) exerts a variety of biological effects including antiviral activity, inhibition of cell or tumor growth and promotion of differentiation of B cells into immunoglobulin-producing cells. In addition to antiviral activity, human IFNG is a potent modulator of immune response and modifies cellular processes. IFNG is classified as immune interferon. IFNG functions as an activating factor to prime macrophages (MAF) for non-specific tumoricidal activity and activates monocytes to exert enhanced cytotoxicity against tumor cells. IFNG acts a a signal for major histocompatibility antigen expression. IFNG boosts cytotoxicity of natural killer cells and stimulates T cell cytotoxicity. The species specificity of IFNG resides in the interaction of IFNG with its receptor. Human IFNG does not bind specifically to mouse, hamster or bovine cells.

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399