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Interferon gamma antibody

Cat. No. GTX10744

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr, Neutralizing/Inhibition

Reactivity

 Mouse, Rat
Package
25 μg ($399)
See all Interferon gamma products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.2 μg/ml
IHC-Fr Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

18 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 5% Trehalose

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

recombinant rat interferon-γ expressed in E. coli.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

interferon gamma , IFNG2

Cellular Localization

Secreted

Background

Interferon gamma (IFNG), a type II or immune interferon, is produced primarily by T lymphocytes and natural killer cells stimulated by alloantigens, tumors, and mitogens. IFNG exerts a variety of biological effects including antiviral activity, inhibition of cell or tumor growth, and promotion of differentiation of B cells into immunoglobulin-producing cells. IFNG, originally characterized based on its antiviral activities, is a potent modulator of immune response and modifies cellular processes. It functions as an activating factor priming macrophages for non-specific tumorcidal activity. IFNG activates monocytes to exert enhanced cytotoxicity against tumor cells. It also boosts cytotoxicity of natural killer cells and stimulates T cell cytotoxicity. IFNG acts as a signal for the major histocompatibility antigen expression system. The species specificity of IFNG resides in the interaction of IFNG with its receptor. Mature IFNG exists as noncovalently linked homodimers. The N-terminal methionyl form of rat IFNG contains 135 amino acid residues and has a predicted molecular mass of approximately 15.5 kDa.

Database

Research Area

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 399