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Involucrin antibody [SY5]

Anti-Involucrin antibody [SY5] used in IHC (Paraffin sections) (IHC-P). GTX72415

Cat. No. GTX72415

Reference 3

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 SY5

Isotype

 IgG1

Application

 ICC/IF, IHC-P, IHC-Fr, ELISA

Reactivity

 Human, Rat, Dog, Pig, Monkey, Gorilla, Owl
Package
500 μl ($239)
See all Involucrin products

APPLICATION

Application Note

ELISA (For coating, order Ab without BSA).

Calculated MW

68 kDa. ( Note )

Positive Control

LS174T Cells, Skin

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.2% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human keratinocytes' involucrin

Purification

Protein A affinity purified

Conjugation

Unconjugated

RRID

AB_383614

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

involucrin

Cellular Localization

Cytoplasm

Background

Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Involucrin antibody [SY5] used in IHC (Paraffin sections) (IHC-P). GTX72415

GTX72415 IHC-P Image

Formalin fixed paraffin embedded human skin stained with Involucrin antibody (cat. # GTX72415).

REFERENCE

Application Reference

Li Z et al. Stem Cell Res Ther 2015; 6 : 17 Rho kinase inhibitor Y-27632 promotes the differentiation of human bone marrow mesenchymal stem cells into keratinocyte-like cells in xeno-free conditioned medium.
Application : ICC/IF
Reactivity : Human
Suarez-Farinas M et al. J Allergy Clin Immunol 2011; 127 (4) : 954-64.e1-4 Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.
Application : IHC-Fr
Reactivity : Human
Biedermann T et al. J Invest Dermatol 2010; 130 (8) : 1996-2009 Human eccrine sweat gland cells can reconstitute a stratified epidermis.
Application : ICC/IF
Reactivity : Human
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 239