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JAK1 (phospho Tyr1022) antibody

Anti-JAK1 (phospho Tyr1022) antibody used in IHC (Paraffin sections) (IHC-P). GTX55099
Anti-JAK1 (phospho Tyr1022) antibody used in Western Blot (WB). GTX55099

Cat. No. GTX55099

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all JAK1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

133 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of JAK1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887913

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Janus kinase 1 , JAK1A , JAK1B , JTK3

Background

This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Database

Research Area

DATA IMAGES

Anti-JAK1 (phospho Tyr1022) antibody used in IHC (Paraffin sections) (IHC-P). GTX55099

GTX55099 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX55099 JAK1 (phospho Tyr1022) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

Anti-JAK1 (phospho Tyr1022) antibody used in Western Blot (WB). GTX55099

GTX55099 WB Image

WB analysis of Ramos (A), Jurkat (B), L929 (C), PC12 (D) whole cell lysates using GTX55099 JAK1 (phospho Tyr1022) antibody.

REFERENCE

Application Reference

Abdou AG et al. J Pathol Transl Med 2018; 52 (6) : 363-368 Immunohistochemistry of Janus Kinase 1 (JAK1) Expression in Vitiligo.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399