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JAK2 antibody

Anti-JAK2 antibody used in Western Blot (WB). GTX31943
Anti-JAK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31943

Cat. No. GTX31943

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all JAK2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

131 kDa. ( Note )

Positive Control

3T3 Cell Lysate

Product Note

JAK2 antibody is predicted to not cross-react with other members of the JAK family of proteins.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

JAK2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human JAK2.The immunogen is located within the last 50 amino acids of JAK2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887636

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Janus kinase 2 , JTK10 , THCYT3

Cellular Localization

Cytoplasm,Nucleus

Background

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-JAK2 antibody used in Western Blot (WB). GTX31943

GTX31943 WB Image

WB analysis of HeLa cell lysate using GTX31943 JAK2 antibody.
Working concentration : 1 μg/ml

Anti-JAK2 antibody used in IHC (Paraffin sections) (IHC-P). GTX31943

GTX31943 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX31943 JAK2 antibody.
Working concentration : 5 μg/ml

REFERENCE

Application Reference

Wu R et al. J Immunother Cancer 2020; 8 (2) SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA.
Lin JT et al. Journal of Functional Foods 2018; 47 : 343-349 Protective effect and mechanism of Muntingia calabura Linn. fruit ethanolic extract against vascular endothelial growth factor production in nickel-stimulated hepatocellular carcinoma cells.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399