GeneTex
United States (US)

JAK3 antibody

Anti-JAK3 antibody used in Western Blot (WB). GTX34020

Cat No. GTX34020

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
ELISA Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

Specificity/Sensitivity

JAK3 Polyclonal Antibody detects endogenous levels of JAK3 protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from human JAK3 around the non-phosphorylation site of Y785.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Janus Kinase 3,Jak-3,Jak3_Human,Jakl,L-Jak,Ljak,Jak3

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-JAK3 antibody used in Western Blot (WB). GTX34020

GTX34020 WB Image

Western Blot (WB) analysis of 293T cells using JAK3 Polyclonal Antibody.

Package List Price ($)
$ 319