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JAK3 antibody

Anti-JAK3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66640
Anti-JAK3 antibody used in Western Blot (WB). GTX66640

Cat No. GTX66640

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

125 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 750-800 of Human JAK3.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Janus kinase 3 , JAK-3 , JAK3_HUMAN , JAKL , L-JAK , LJAK

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-JAK3 antibody used in IHC (Paraffin sections) (IHC-P). GTX66640

GTX66640 IHC-P Image

IHC-P analysis of human brain tissue using GTX66640 JAK3 antibody.

Anti-JAK3 antibody used in Western Blot (WB). GTX66640

GTX66640 WB Image

WB analysis of various samples using GTX66640 JAK3 antibody.
Lane1 : HEK293T whole cell lysate
Lane2 : sp2/0 whole cell lysate
Lane3 : PC12 whole cell lysate
Dilution : 1:500

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf