*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The peptide used to generate this antibody is available for purchase (GTX88380-PEP).
Mouse, Rat, Dog, Pig(>80% identity)
Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.
Peptide with sequence C-QPSARSEGEFKQTS, from the C Terminus of the protein sequence according to NP_058642.1.
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
KAT Antibody , F11R Antibody , JAM1 Antibody , JAMA Antibody , JAM Antibody , JCAM Antibody , PAM1 Antibody , CD321 Antibody
Localized at tight junctions of both epithelial and endothelial cells.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
GTX88380 WB Image
WB analysis of human peripheral blood mononucleocyte lysate using GTX88380 JAM-A antibody, C-term.
Dilution : 0.3µg/ml
Loading : 35µg protein in RIPA buffer