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JAM-C antibody [4M35]

Cat No. GTX52881

Host

Mouse

Clonality

Monoclonal

Clone Name

4M35

Isotype

IgG1

Application

WB, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

35 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant JAM-C

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

JAM2 , JAM3 , JAMC , junctional adhesion molecule 3 , CD323 , Junctional Adhesion Molecule C , JAM-C

Cellular Localization

Cell membrane,Cell junction,Desmosome,Secreted,Extracellular space

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]

Database

Research Area

REFERENCE

There are currently no references for JAM-C antibody [4M35] (GTX52881). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for JAM-C antibody [4M35] (GTX52881). Be the first to share your experience with this product.
SDS
PBS.pdf