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Jab1 antibody

Anti-Jab1 antibody used in Western Blot (WB). GTX55683
Anti-Jab1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55683
Anti-Jab1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55683

Cat. No. GTX55683

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Jab1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

38 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human COPS5 (NP_006828.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

COP9 signalosome subunit 5 , CSN5 , JAB1 , MOV-34 , SGN5

Cellular Localization

Cytoplasm, cytosol,Nucleus

Background

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Jab1 antibody used in Western Blot (WB). GTX55683

GTX55683 WB Image

WB analysis of various sample lysates using GTX55683 Jab1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Jab1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55683

GTX55683 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX55683 Jab1 antibody.
Dilution : 1:100

Anti-Jab1 antibody used in IHC (Paraffin sections) (IHC-P). GTX55683

GTX55683 IHC-P Image

IHC-P analysis of human liver tissue using GTX55683 Jab1 antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399